Tn7::In2-8 dispersion in multidrug resistant isolates of Acinetobacter baumannii from Chile.
نویسندگان
چکیده
Acinetobacter baumannii is considered an important pathogen in our hospital environment having a well-known capacity to acquire different mechanisms of antibiotic resistance. Previous studies in our laboratory had exposed the high dispersion of class 2 integrons in this species. In the present study, we analyzed 7 multiresistant intI2 positive A. baumannii isolates, 6 of which were found to harbour the Tn7::In2-8 element. Our results demonstrate the unusually high distribution of Tn7::In2-8 among different A. baumannii clones from Chile, suggesting a particular behavior of these elements at geographical level.
منابع مشابه
Novel rearrangement of a class 2 integron in two non-epidemiologically related isolates of Acinetobacter baumannii.
Tn7::In2-8 contains sat2-aadB-catB2(deltaattC)-dfrA1-sat2-aadA1-orfX in the variable region of a class 2 integron embedded in the Tn7-like transposon. This novel transposon was inserted in its preferred site downstream of the glms gene in Acinetobacter baumannii. Acquisition of the pseudocassette catB2 could have arisen by a secondary-site integrase-mediated intermolecular recombination event.
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ورودعنوان ژورنال:
- Revista Argentina de microbiologia
دوره 42 2 شماره
صفحات -
تاریخ انتشار 2010